Primary infection with HHV-6 may be asymptomatic, or it may cause the exanthem subitum/roseola syndrome. Within that complex, otitis. Roseola infantum is also known as exanthema subitum or sixth disease according to the childhood exanthem classification after measles, scarlet fever, rubella. Exanthema subitum (roseola infantum) is one of the mildest exanthematous diseases to which infants under 2 years are subject. It possesses, however.

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The primary variant that causes roseola infantum is HHV-6B.

Before the age of three [1]. Create a free personal account to download free article PDFs, sign up for alerts, customize your interests, and more.

In rare cases, HHV-6 can become active in an adult previously infected during childhood and can show signs of mononucleosis.

Where can I get more information? The majority of cases of roseola infantum are mild and self-limited.

There is no specific vaccine against or treatment for exanthema subitum, and most children with the disease are not seriously ill. It begins with a high fever that may exceed 40 C F. Get free access to newly published eksantemw. Fever followed by rash [1].

Affilations 1 Lewis Gale Hospital – Montgomery.


Roseola (Exanthema Subitum) – Health Topics – Southern Nevada Health District

Purchase access Subscribe to the journal. The rash phase of roseola generally follows the disappearance of the fever. A fever, sometimes subitu, high as F, appears suddenly and lasts days. In other projects Wikimedia Commons. Second cases of roseola are rare.

Serum levels of matrix metalloproteinase-9 and tissue inhibitor of metalloproteinases-1 in human herpesvirusinfected infants with or without febrile seizures. Viral cutaneous conditions, including viral exanthema B00—B09— Turn recording back on. Retrieved 26 September Most commonly, the disease occurs in children between the ages of 6 months and 2 years of age. Treatment is supportive with rest, maintaining fluid intake and antipyretics such as acetaminophen or ibuprofen to control the fever.

Roseola infantum and its causal human herpesviruses. In most cases, the disease is diagnosed based on the appearance of the fever followed by a rash as described above.


HHV-6 will likely remain latent in immunocompetent patients but can be a major cause subotum morbidity and mortality in patients who are immunosuppressed. Due to the rash likely being nonpruritic, treatment is unnecessary.

Reactivation of the virus can occur in immunosuppressed patients. It is not fully known how the virus is spread, but research suggests that contact with the saliva of an infected individual may be the most likely source of infection.


Review The spectrum of human herpesvirus 6 infection: Sign in to make a comment Sign in to your personal account. Sign in to save your search Sign in to your personal account.

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Roseola – Wikipedia

What can be done to prevent the spread of roseola? Measures to effectively control roseola have not been developed.

Sign in to customize your interests Sign in to your personal account. In rare cases, this can cause febrile convulsions also known as febrile seizures or “fever fits” due to the sudden rise in body temperature, but in many cases the child appears normal. Review Roseola infantum and its causal human herpesviruses.

Rubella virus Rubella Congenital rubella syndrome “German measles” Alphavirus infection Chikungunya fever. The subiutm typically lasts three to five days.

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