Croton macrostachyus. Euphorbiaceae. Hochst. ex Ferret et Galinier. C. macrostachys: A representative tree at. Kakuzi Ranch, Kenya. (Paul K.A. Konuche). Croton macrostachyus Hochst. ex Delile is a species of the genus Croton L., Euphorbiaceae family, commonly known as the spurge family. In Kenya, leaves and roots from Croton macrostachyus are used as a traditional medicine for infectious diseases such as typhoid and measles.
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The soaked extract was separated from the plant residue using a Buchner funnel. An acute toxicity test was carried out to ascertain the safety of the extract.
This article has been cited by other articles in PMC. The exceptions were the isobutanol extract in both antimalarial tests and the ethyl acetate extract in the Peters’ suppressive test.
For the cytotoxicity study, the aqueous and organic extracts were administered to larvae of Artemia spp. Antimicrobial and cytotoxic constituents from leaves of Sapium baccatum.
Nutrient composition and short-term release from Croton macrostachyus Del. Abstract There is an increasing need for innovative drug and prophylaxis discovery against malaria. Spices, condiments and medicinal plants in Ethiopia, their taxonomy and agricultural significance.
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Medicinal plants of East Africa. There is cross-cultural agreement among ethnomedicinal uses of C. The methanol extract was not active against L. Each mouse was infected intraperitoneally by injecting 0.
View at Google Scholar J. Journal of Ethnopharmacology 45 1: Anthony, Croton macrostachyus Hochst. This upholds folkloric use of the plant and the earlier studies mmacrostachyus out with leaves, root, and fruit.
Similarly, Aleme et al. The zones of inhibition mm were recorded from measurements of the clear zones around the agar wells.
A bark infusion is taken to treat chest problems and rheumatism. Mqcrostachyus stem bark extracts were prepared as described before [ 19 ]. The crude methanol extract of C. The extracts showed taenicidal activity in volunteers with tapeworm infection. Chloroform and n-butanol fractions of C. In another study, Mohammed et al. The survival of the mice in all the groups was checked twice a day.
Two labdane diterpenoids and a seco-tetranortriterpenoid from Turreanthus africanus. Materials and Methods 2.
In Ethiopia the leaves of Croton macrostachyus are attacked by a leaf spot caused by the fungus Cylindrosporium sp. Evaluation of the antimalarial activity of plants used by the Tacana Indians. Leaf decoction, infusion, or maceration, stem or root bark, and leaf sap of C.
macrostachyu As a source of novel drugs, plants remain grossly understudied and underused, especially in the developed world [ 23 ]. World Health Organization; Acute Toxicity Experiment The results macrosachyus the toxicity experiment showed that all animals in the ethyl acetate, methanol, and water extract groups were normal during the observations and at the end of the study period. The experiments were carried out using triplicate samples. A leaf decoction is also taken to treat cough and stomach problems.
Antimalarial Activity of Croton macrostachyus Stem Bark Extracts against Plasmodium berghei In Vivo
Croton macrostachyus Croton macrostachyus x – 84k – jpg www. In Kenya and Tanzania a root infusion is taken to treat intestinal parasites.
View at Google Scholar G. Biochim Biophys Acta Antibacterial and anti-inflammatory activities of some plants used for medicinal purposes in Kenya. Treatment of falciparium malaria with quinine and tetracycline or combined mefloquine-sulfadoxinen-pyrimethaminen on the Thai-Kamputchean border. The seed oil is a very powerful purgative.
Our results show that between the bacterial strains there is variation in susceptibility to extracts. In vitro evaluation of Albiziagummifera and Croton macrostachyus against clinical isolates of Neisseria gonorrhoae.
This study was funded by the Academy of Finland, Grant no. Trees on farms and their contribution to soil fertility parameters in Badessa, eastern Ethiopia. Physical and behavioral observations of the experimental mice did not show any visible signs of overt toxicity such as lacrimation, loss of appetite, tremors, hair erection, salivation, and diarrhoea. The ethanol stem bark extract demonstrated some activity with the minimum fungicidal concentration MFC values ranging from The broadest effect against all the studied bacteria in a dose-dependent manner was achieved by the ethyl acetate extract.
Citation in web searches. The DMSO negative control had no inhibitory activity. Carbon number Sample ppm Lupeol ppm 28 The seeds are sown in a mixture of sand and compost 1: Annals of Tropical Medicine and Parasitology. These pharmacological activities include anthelmintic [ 3095 ], antibacterial [ 535562859296 — ], anticonvulsant and sedative [ 50 ], antidiabetic [ 88 ], antidiarrhoeal [ 24 ], antifungal [ 628692], anti-inflammatory [ 84], antileishmanial [ 94 ], antioxidant [ 86 ], antiplasmodial [ 8789, ], antimycobacterial [ ], larvicidal [ 1950 ], and cytotoxicity [ 27437396— ].