Can J Infect Dis Med Microbiol. Mar-Apr;26(2) Empyema caused by Clostridium bifermentans: A case report. Edagiz S(1), Lagace-Wiens P(2), Embil . Clostridium bifermentans bacteremia resulting in metastatic osteomyelitis involving the sacrum, spine, and ribs. The emergence of resistance of this organism to. We report a case of recurrent Clostridium bifermentans bacteremia resulting in metastatic osteomyelitis involving the sacrum, spine, and ribs. The emergence of .

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Positive immunohistochemical staining dark pink for Clostridium species within areas bifermentwns endometrial necrosis. Three days later, she was hospitalized after multiple syncopal events at home.

Tobramycin, clindamycin, and doxycycline bifermentabs added for sepsis. On the third day postadmission, the patient continued to complain of significant dyspnea and chest pain.

Can J Dis Med Microbiol ; Clostridium sordellii also elaborates lethal toxin, which undermines the actin cytoskeleton at the cellular level, and is believed through this activity to compromise endothelial barrier integrity [ 18 ]. It is found in sewage, soil, and occasionally the intestinal flora of humans. C bifermentans is an anaerobic, spore-forming, Gram-positive bacillus.

Pelvic examination showed no cervical motion tenderness, cervical discharge, or other abnormality. His antimicrobial therapy was changed to a combination of piperacillin-tazobactam and levofloxacin, and heparin was initiated as treatment for the pulmonary embolus.


Septic arthritis of the knee due to Clostridium bifermentans. Am Rev Respir Dis. J Bone Joint Surg Am ; Blood smear showed marked neutrophilia and no evidence of hematologic malignancy.

A CT scan of bifermentzns chest was performed with contrast and this demonstrated a right main pulmonary artery embolus. Gorbach SL, Thadepalli H. Evaluation of cases.

Support Center Support Center. This page was last edited on 10 Marchat Open Forum Bifermejtans Dis. The isolate was susceptible to amoxicillin-clavulanate, cefoxitin, clindamycin, meropenem, metronidazole and penicillin. The patient was admitted to hospital.

The etiology of the pneumothorax in the present case also remains uncertain, as is its association if any with the development of infection. She subsequently deteriorated in hospital, with repeat chest radiography demonstrating pulmonary infiltrates and a pneumothorax that appeared ckostridium communicate with a cavitary lesion in the chest.

Report of a case caused by Clostridium bifermentans and review of the literature.

Isolation of Clostridium tetani from anaerobic empyema. The patient clinically deteriorated and ultimately required admission to the intensive care unit. Clostridium species are ubiquitous in the environment.

Empyema caused by Clostridium bifermentans: A case report.

Pleural empyema due to Clostridium difficile and Clostridium cadaveris. Voth D, Ballard J. From Wikipedia, clkstridium free encyclopedia. Pencek T, Burchiel K. Case report and review of the clostriidum.

Prosthetic valve endocarditis due to Clostridium bifermentans: This article has been cited by other articles in PMC. Please review our privacy policy. Thus, to remove potential toxin, empiric plasmapheresis was started on hospital day 3, which showed immediate improvement in hemodynamics, and fluid was able to be removed with continuous venovenous hemofiltration.


Taxonomy of Clostridium bifermentans and Clostridium sordellii I. He was otherwise hemodynamically stable. Septic arthritis of the knee due to Clostridium bifermentans. Lethal toxin clostridikm a marked propensity for inducing rapid morbidity and contributes to the profound capillary leak, hemoconcentration, and toxic shock syndrome often seen in C sordellii infections [ 19 ].

Clostridium bifermentans – Global Catalogue of Microorganisms

Our patient had an endometrial ablation 5 months before her presentation, which was felt to be too distant in time to be a definitive clostfidium factor. Bacteriol Rev ; Histopathology showed bifermentabs of the uterus, a site of infection not previously described. She also developed large bilateral pleural effusions and required bilateral chest tube placement with 4 liters per day transudative fluid output.

Of note, however, genetic exchange between large toxin protein producing strains of Clostridium has been previously suggested [ 20 ].

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